
Course Description
Our active learning approach, through discussions, group work, and applied exercises, ensures deep engagement and long-term retention.
Who is this course for?
This course is designed for all healthcare professionals who are looking to enter the field of clinical research or strengthen their skills in interpreting and working with clinical studies. This includes:
- Residents
- Fellows
- Attending physicians
- Medical students
- Other healthcare professionals
- Clinician-scientists
Designed for use across specialties
The course covers core principles of clinical research and is structured to be accessible and relevant regardless of medical specialty. It is suitable for fields such as:
- Internal Medicine
- Family Medicine
- Surgery
- Anesthesiology
- Gynecology
- Pediatrics
- Neurology
- Psychiatry
- as well as all other disciplines
Course Details
Earn a certificate that reflects excellence, awarded by NEJM Group & AMBOSS.
English
Step-by-step skills development with interactive quizzes, practice questions (MC), NEJM articles, AMBOSS chapters, and more
By the end of this course, you will be able to:
- Understand why specific study designs are chosen for research questions
- Apply key concepts of biostatistics and epidemiology to study design
- Define exposure, intervention, comparator, and primary outcomes in a trial
- Formulate a clear, testable hypothesis
- Confidently interpret and evaluate high-impact clinical research
- Identify study limitations and their implications for practice
- Develop a fundamental understanding of the design, analysis, and interpretation of clinical research
- Equip learners with the skill set required to evaluate and apply the evidence
- Improve study design rigor and enhance clinical research careers
Course Director
Renowned Harvard clinician-educator with global research and teaching experience
Dr. Kenneth Christopher is a nephrologist, intensivist, clinical scientist, and Assistant Program Director of the Internal Medicine Residency Program at the Brigham and Women’s Hospital. Trained in clinical trials, epidemiology, and critical care outcomes at the Harvard T.H. Chan School of Public Health, he combines rigorous research expertise with a global teaching perspective, having led education programs across the US, UK, and Asia. Widely published and recognized with multiple national awards, Dr. Christopher is also celebrated for his excellence in teaching and mentorship at Harvard Medical School.
Dr. Jamie M. Robertson is an Assistant Professor of Emergency Medicine at Harvard Medical School and a Senior Research Scientist at the STRATUS Center for Medical Simulation at Brigham and Women’s Hospital. Her funded research (NASA, NSF, NIH) focuses on improving patient safety in clinical spaces using simulation-based methods. Primarily, her focus is on nontechnical skills, including communication and leadership, for health care teams. Nationally, she is a former Associate Editor for the Healthcare Simulation Dictionary and a leader in simulation design and implementation. She is among the first 50 individuals to earn the designation of Certified Healthcare Simulation Educator-Advanced, and she is a Fellow of the Academy of Simulation in Healthcare. Dr. Robertson completed her undergraduate education at Seattle University before earning her MPH in Behavioral and Community Health Sciences and PhD in Epidemiology from the University of Pittsburgh Graduate School of Public Health.

Core Concepts in Clinical Research
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This course was developed jointly by physician-authors and editors at AMBOSS and NEJM Group, without commercial support, and in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.
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